邁威生物衝刺港股 國產Nectin-4 ADC領跑者蓄勢待發

香港, 2026年4月20日 - (亞太商訊 via SeaPRwire.com) - 4月20日,中國創新製藥企業邁威(上海)生物科技股份有限公司(以下簡稱“邁威生物”)正式啟動港股招股。若成功登陸港股,公司將形成“A+H”雙平臺佈局,進一步拓寬融資管道,加速其創新藥全球開發與商業化進程。邁威生物是一家全產業鏈佈局的創新型生物製藥公司,專注于自主開發腫瘤和年齡相關疾病藥物,覆蓋腫瘤、免疫、眼科、骨科等領域。公司成立於2017年, 2022年在上海證券交易所科創板上市(股票代碼:688062)。核心產品9MW2821:國產Nectin-4 ADC領跑者邁威生物的核心產品9MW2821(BFv)是一款靶向Nectin-4的抗體偶聯藥物(ADC),目前正處於多項關鍵III期臨床試驗階段。根據弗若斯特沙利文的資料,9MW2821是中國開發用於治療尿路上皮癌的所有靶向Nectin-4 ADC中進展最快的產品,全球範圍內僅次於已獲FDA批准的Padcev。更值得關注的是,9MW2821是全球首款進入宮頸癌關鍵III期試驗階段的靶向Nectin-4 ADC。該產品已獲得美國FDA三項快速通道認定及一項孤兒藥資格認定,並獲得中國國家藥監局兩項突破性療法認定。從臨床資料來看,9MW2821的療效表現亮眼。截至2024年10月,在既往接受過鉑類化療及PD-(L)1抑制劑治療的晚期尿路上皮癌患者中,9MW2821單藥治療的客觀緩解率(ORR)達到62.2%,疾病控制率(DCR)高達91.9%,中位無進展生存期(PFS)為7.4個月,中位總生存期(OS)為14.6個月。在三陰乳腺癌患者中,ORR達到50.0%,DCR為80.0%。截至2025年4月,接受9MW2821作為一線治療的40名可評估療效的尿路上皮癌患者中,ORR為87.5%、cORR為80%、DCR為92.5%,中位PFS為12.5個月。目前,公司正在中國推進9MW2821作為單藥或聯合特瑞普利單抗治療尿路上皮癌、以及單藥治療宮頸癌的多項III期試驗,同時在美國開展針對三陰乳腺癌的單藥I期研究。差異化管線佈局:ADC+非ADC雙輪驅動除核心產品外,邁威生物已建立覆蓋腫瘤、免疫、骨科、眼科等領域的豐富管線組合,包括4款已上市產品及10款候選藥物(1款處於NDA階段、8款處於臨床階段、1款處於臨床前階段)。在ADC領域,公司構建了一組多元化的創新ADC。其中,靶向B7-H3 的 7MW3711,已獲FDA授予小細胞肺癌孤兒藥資格,早期臨床資料顯示良好安全性與耐受性,並於2026年2月啟動聯合JS207(PD-1/VEGF雙抗)的Ib/II期試驗;靶向CDH17的新一代ADC 7MW4911在臨床前研究中表現出高效內化與選擇性殺傷特性,針對晚期實體瘤的單藥療法已於2025年11月在中國啟動I期臨床,2026年1月在美國啟動I/II期臨床。非ADC管線方面,9MW1911是中國首款自主研發的靶向非Th2通路的COPD大分子藥物,II期資料顯示中重度COPD急性加重年化發生率較安慰劑組降低超30%,全球ST2靶點臨床進度位元列第二;9MW3811是首款進入病理性瘢痕治療臨床階段的IL-11靶向藥物,臨床試驗顯示具有良好的安全性,且在人體中的半衰期最長可達30天。近期,公司宣佈中國國家藥品監督管理局受理靶向 LILRB4/CD3 TCE 雙抗6MW5311 的IND申請,該品種美國臨床試驗申請目前處於 pre IND 階段,計畫於 2026 年第二季度向 FDA 正式遞交申請。憑藉核心管線的臨床進度優勢和差異化的ADC組合,邁威生物正加速向全球化創新製藥企業邁進。技術平臺構築競爭壁壘邁威生物建立了具有自主智慧財產權的四大核心ADC技術,涵蓋DARfinity(定點偶聯工藝)、IDconnect(連接子分子)、Mtoxin(新型毒性分子)及LysOnly(有條件釋放結構)。這四項專有技術構成了公司定點偶聯ADC開發平臺鏈間二硫化物藥物偶聯(「IDDC」)的支柱。基於IDDC平臺,9MW2821通超載藥連接子與人源化靶向Nectin-4單抗之間的二硫鍵形成雙位點偶聯。與Padcev相比,9MW2821擁有穩定的連接子和均一的DAR,使其在血液迴圈中更加穩定,從而更有效地遞送到腫瘤細胞,表現顯著優於傳統非定點偶聯ADC產品。此外,公司還擁有一體化高效抗體發現平臺和TCE雙/三特異性抗體開發平臺,為持續創新提供技術支撐。商業化能力初顯,國際化步伐加快截至2025年12月31日,邁威生物在中國建立了覆蓋327個城市、8,000多家醫院的分銷網路,擁有127名分銷商。2025年公司實現收入6.59億元人民幣,同比增長230%,主要得益於藥品銷售及對外授權收入增加。國際化方面,公司已與Disc、Calico、齊魯製藥等多家國內外領先藥企達成許可合作。其中,與Disc就9MW3011達成獨家許可,潛在里程碑付款達4.1億美元;與Calico就9MW3811達成獨家許可,潛在里程碑付款近6億美元;與齊魯製藥就邁粒生®達成獨家許可,首付款及里程碑付款合計最高達5億元人民幣;並與Kalexo Bio就研發新型雙靶點siRNA候選藥物訂立獨家授權合約。儘管2025年淨虧損仍達9.72億元人民幣(主要由於研發投入高達9.77億元),但公司收入結構持續優化,對外授權收入占比從2024年的27.6%提升至2025年的62.0%。截至2025年末,公司持有現金及銀行結餘約15.27億元人民幣,研發管線穩步推進。在商業化落地方面,公司已取得實質進展。目前,邁威生物已有三款商業化的生物類似藥產品,即邁利舒®、邁衛健®及君邁康®,2025年合計貢獻銷售收入約2.48億元人民幣。公司未來還將獲得邁粒生®的銷售額最高兩位數百分比的特許權使用費,進一步增長值得期待。結語總體而言,邁威生物憑藉差異化的ADC管線、扎實的技術平臺、日益完善的商業化網路以及積極的國際化戰略,正加速向全球化商業階段邁進。若H股成功上市,公司將獲得更充足的資金彈藥,有望在ADC這一黃金賽道上加速奔跑。 Copyright 2026 亞太商訊 via SeaPRwire.com. All rights reserved. www.acnnewswire.com
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Chilean Supreme Court orders broader blocking of mirror gambling sites iGame

Chilean Supreme Court orders broader blocking of mirror gambling sites

(AsiaGameHub) - Chile’s Supreme Court has issued a ruling requiring telecommunications service providers to block access not only to primary gambling websites, but also to these operators’ secondary mirror sites. This decision notably bolsters government efforts to eliminate illegal online gambling across the country. Prior to this Supreme Court verdict, a ruling from the Santiago Appeals Court had found that telecom companies had fulfilled their required obligations. That lower court concluded that the firms had successfully blocked access to the main domains of unlicensed gambling operators. The case originated from a legal action aimed at forcing major telecom providers including Claro, Entel, GTD, Movistar, WOM, and VTR to restrict access to gambling websites that are currently illegal to operate in Chile. While the telecom companies had complied with orders to block access to the primary URLs of targeted sites, they argued that restricting access to secondary mirror sites would present technical challenges and carry a risk of unintended disruptions to other unrelated internet services. The Appeals Court agreed with this argument, ruling that only primary domains needed to be blocked under existing orders, and closed the case as resolved. The Supreme Court rejected the reasoning put forward by the Appeals Court. It determined that prior rulings had not been sufficiently implemented, leaving unlicensed gambling services accessible to users because the original blocking orders had only been partially carried out. The Supreme Court also pointed out an additional error in the lower court’s ruling: the Appeals Court had stated that full enforcement of the blocking orders was impracticable, while at the same time declaring the matter fully resolved and closed. In a notable development, the Supreme Court upheld a complaint against the appellate judges, citing “serious fault or abuse” in their handling of the case. This move underscores the top court’s strict stance on ensuring effective enforcement for matters involving unregulated digital activity. The case has now been sent back to the Court of Appeals for reconsideration, with explicit instructions to guarantee full compliance with all required blocking measures. Under the Supreme Court’s revised interpretation of the requirements, telecom companies are now obligated to: Identify and block mirror and alternative domains operated by illegal gambling platforms Ensure that access restrictions are applied to more than just primary URLs of targeted sites Roll out more comprehensive technical measures to prevent users from circumventing the blocks Wider Implications By mandating the blocking of both primary and mirror sites for illegal gambling operators, Chile’s Supreme Court has set a new precedent for digital regulation enforcement. The decision reflects a shift toward stricter regulatory oversight, and signals that partial compliance will no longer be considered acceptable when addressing unlicensed online gambling. This article is provided by a third-party. AsiaGameHub (https://asiagamehub.com/) makes no warranties regarding its content. AsiaGameHub delivers targeted distribution for iGaming, Casino, and eSports, connecting 3,000+ premium Asian media outlets and 80,000+ specialized influencers across ASEAN.
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Google bans 270M+ gambling ads in 2025 as regulatory pressure mounts iGame

Google bans 270M+ gambling ads in 2025 as regulatory pressure mounts

(AsiaGameHub) - Google has removed hundreds of millions of gambling-related advertisements for violating its policies, with the tech company noting that its safety teams are operating around the clock. Despite these efforts, Google, along with other major technology firms, continues to face regulatory scrutiny regarding the promotion of illegal gambling across various international markets. The Alphabet subsidiary has been utilizing its Gemini AI technology to identify "bad ads"—promotions on the Google Ads network that fail to meet its standards. In 2025, the company blocked or took down 8.3 billion advertisements, a figure roughly equivalent to one banned ad for every person on Earth, based on April 2026 Worldometer projections. Gambling and gaming represented the eighth-largest category of prohibited advertisements, with more than 270.7 million ads removed in 2025. Additionally, the sector accounted for 123.9 million restricted ads, making it the third-largest category in that segment. “Our teams have long used advanced AI to identify and stop scammers, and Gemini takes that work even further,” stated Keerat Sharma, Google’s Vice President and General Manager of Ads Privacy and Safety. “Our models analyse hundreds of billions of signals — including account age, behavioural cues and campaign patterns — to stop threats before they reach people. “Unlike earlier keyword-based systems, our latest models better understand intent, helping us spot malicious content and preemptively block it, even when it’s designed to evade detection.” Whose ads have been removed?… Gambling advertising has increasingly become a focal point for Google over the past year, driven by rising public and political pressure regarding the visibility of betting content—both legal and illegal—across multiple regions. In response to concerns raised in countries including the UK, Brazil, the Netherlands, and Australia, Google has taken action. In January, Google Ireland announced that its advertising policies would be tightened starting in March 2026. The Google Ads team in Ireland informed stakeholders that accounts experiencing repeated policy violations or certification revocations could face permanent loss of certification or the rejection of future applications. Google’s 2025 report also highlighted significant enforcement against publishers, noting 9.7 million policy violations by gambling and gaming publishers, ranking the sector fifth in terms of page volume. However, the report does not clarify whether the gambling platforms being promoted were licensed or unlicensed within their respective target markets. This distinction is critical for gambling regulators demanding accountability from tech companies. The prevalence of unlicensed advertising on social media has been a frequent subject of debate in the UK, particularly regarding regulation and taxation. Meanwhile, in Brazil, the nascent "Bets" market continues to contend with a long-standing black market that existed for decades prior to the formal legalization of the sector on January 1, 2025. On Saturday, April 18, the Brazilian Ministry of Justice and Public Security (MJSP) issued letters to Google Brazil and Apple, demanding clarification regarding the presence of illegal betting applications on the Google Play Store and Apple’s App Store. According to the MJSP, these applications were not licensed by the Secretariat of Prizes and Bets (SPA), the betting regulator under Brazil’s Ministry of Finance. The apps were identified through monitoring conducted by the General Coordination of Rating Classification of the National Secretariat of Digital Rights (SEDIGI). The MJSP has requested that Google and Apple provide comprehensive details regarding their internal policies, screening processes, and an updated inventory of all lottery, betting, and casino applications available on their platforms. Pressure remains high on Big Tech firms like Google and Apple, as well as social media platforms like Meta and X, to curb the spread of online gambling. Regulators in markets such as the UK and Brazil have also highlighted the use of influencers to promote illegal gambling products. Nevertheless, Google maintains confidence in its ability to police its advertising platform. Emphasizing the effectiveness of the Gemini AI system, Sharma noted that the technology has “dramatically improved our ability to detect and stop bad ads”. “Our systems caught over 99% of policy-violating ads before they ever served, and we’re continuing to evolve our defenses to stay ahead of even the most advanced schemes,” Sharma asserted. This article is provided by a third-party. AsiaGameHub (https://asiagamehub.com/) makes no warranties regarding its content. AsiaGameHub delivers targeted distribution for iGaming, Casino, and eSports, connecting 3,000+ premium Asian media outlets and 80,000+ specialized influencers across ASEAN.
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A PLAYER TURNS A $0.20 BET INTO $3,000 CAD WITH A 15,000× PAYOUT IN 7RINGS GAMING’S SLOT MAYAN APOCALYPTO iGame

A PLAYER TURNS A $0.20 BET INTO $3,000 CAD WITH A 15,000× PAYOUT IN 7RINGS GAMING’S SLOT MAYAN APOCALYPTO

(AsiaGameHub) - 7Rings Gaming has reported a significant win on its ‘Mayan Apocalypto’ slot, with a player achieving a payout of 15,000 times their initial bet. This remarkable win saw a player transform a 0.20 Canadian dollar wager into 3,000 Canadian dollars during a single gaming session. This payout matches the game's highest possible multiplier. A full replay of the winning session is available via the provided link. Mayan Apocalypto is a high-volatility slot game that immerses players in a mystical ancient Mayan temple setting. The game features a 5x5 grid and blends traditional payline structures with contemporary gameplay elements, including dynamic Wild symbols and multipliers within the bonus rounds. 7Rings Gaming is a rapidly expanding iGaming studio, boasting a portfolio of 18 titles and releasing between one and three new games each month. The company serves a client base of over 300 operators worldwide, including prominent industry brands. The studio's strategy centers on developing distinctive, character-focused games that combine striking visual design with features aimed at enhancing player engagement. These features include leaderboards, indicators for 'hot' and 'cold' game states, and the functionality to share replays of substantial wins. This article is provided by a third-party. AsiaGameHub (https://asiagamehub.com/) makes no warranties regarding its content. AsiaGameHub delivers targeted distribution for iGaming, Casino, and eSports, connecting 3,000+ premium Asian media outlets and 80,000+ specialized influencers across ASEAN.
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Stake’s March 2026 Performance Report: Key Moments from Casino and Sports Betting iGame

Stake’s March 2026 Performance Report: Key Moments from Casino and Sports Betting

(AsiaGameHub) - March 2026 saw notable activity for Stake, with high volumes of player engagement across both its casino game library and sports betting platform. Players showed strong interest in exploring a wide range of offerings that month, including exclusive titles such as Bank Basher and Waylanders Forge, alongside fresh gaming experiences. One of the key milestones for Stake in March was the launch of the new Moles casino game, marking another expansion of the platform's content portfolio. The Stake Engine community sustained its already high levels of player participation across both the official Forum and Discord server. Beyond these updates, Stake also secured two major partnerships in March: one with Astralis, a leading esports organization, and another with professional footballer Eden Hazard. Lastly, a new feature called WinSAFE has rolled out exclusively for Twist Gaming slots, making its first appearance alongside the new Cult of Cash WinSAFE slot title. Casino & Sports Betting Performance Stake logged a total of 7.83 billion casino bets in March, averaging over 2,900 bets placed each second. Most popular category: Slots (2.26 billion bets) Top Stake Original: Dice (2.23 billion bets) Notable large wins: $9.7 million payout on Le Fisherman $1.1 million record for highest single bet payout on Sugar Rush 1000 For the sportsbook segment: 70.25 million total bets placed across all sports Largest payout: $1.8 million (from the LA Lakers vs Houston Rockets matchup) Most popular sport category: Soccer (35.8 million bets, making up over 50% of total sports wagers) Most Popular Casino Offerings Top Performing Slot Games Pragmatic Play claimed all five top spots in the slot game rankings: Joker’s Jewels Gates of Olympus 1000 Sweet Bonanza 1000 Big Bass Rock and Roll Gates of Olympus Super Scatter Top New Game Releases Rabbit Heist Mummy’s Jewels 100 Gift Bonanza Big Bass Raceday Repeat Le Bunny Top Live Casino Offerings Crazy Time Ice Fishing Stake Roulette Roulette Lobby Stake Exclusive Speed Baccarat 1 Top Stake-Exclusive Games Bank Basher — 32.7M bets Waylanders Forge — 29.7M bets Big Bass BOOM — 14.2M bets Sweet Fiesta — 14.1M bets Dragonspire — 13.6M bets Top Performing Stake Engine Games Wings of Valhalla — 8.7M bets Sword Drop — 8.1M bets Orbs of Magic — 7.5M bets Wild Frontier — 7.2M bets LepreCash — 7.1M bets Most Popular Game Providers Stake Originals Pragmatic Play Hacksaw Gaming NoLimit City Twist Gaming Stake continues to offer a range of educational resources for both casino gaming and sports betting users, including beginner tutorials, strategy guides, and clear odds explanations. Players also have access to ongoing promotions, VIP loyalty rewards, and community-focused challenges to enhance their overall platform experience. Stake prioritizes responsible gambling via its Stake Smart toolkit, which includes budgeting functionalities and support resources designed to help users maintain control over their gaming activity. This article is provided by a third-party. AsiaGameHub (https://asiagamehub.com/) makes no warranties regarding its content. AsiaGameHub delivers targeted distribution for iGaming, Casino, and eSports, connecting 3,000+ premium Asian media outlets and 80,000+ specialized influencers across ASEAN.
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PartnerMatrix Becomes Panel Sponsor at AffPapa Conference Madrid iGame

PartnerMatrix Becomes Panel Sponsor at AffPapa Conference Madrid

(AsiaGameHub) - AffPapa is thrilled to share that PartnerMatrix will be joining the AffPapa Conference Madrid 2026 as a Panel Sponsor and will also be exhibiting at booth №12. PartnerMatrix is a highly decorated affiliate and agent management platform built for iGaming, used by over 250 operators across various markets to boost customer acquisition and enhance performance. This software covers everything from real-time statistics and transparent reporting to flexible multi-tier commission structures and full program oversight. Customizable for different regions and supported by 24/7 assistance, PartnerMatrix enables teams to launch, scale, and refine their affiliate operations without the typical complexities. PartnerMatrix issued a statement saying: PartnerMatrix will be attending the AffPapa Conference in Madrid as both an exhibitor and panel sponsor. Our CEO, Vahe Khalatyan, will join the “The CEO Toolkit: Scaling, Structuring & Winning in Competitive Markets” panel, sharing his expert insights during the discussion. Stop by booth №12 to learn how PartnerMatrix supports affiliate marketing setup and expansion through software, data-driven intelligence, and strategic execution. If scaling your business in competitive markets is your top priority, this is the ideal place to launch that conversation. Hosted from May 18 to May 20 at the Novotel Madrid Center, AffPapa Conference Madrid will welcome more than 1,500 industry professionals, with a demographic split of 40% affiliates, 40% operators, and 20% B2B providers. The full three-day agenda includes pre-conference side events, speed-dating sessions, panel discussions, an AI workshop presented by createIT, the 2026 AffPapa iGaming Awards ceremony, plus a closing party hosted with DJ Kryoman. Yeva Avagyan, Head of Commercial at AffPapa, noted: With PartnerMatrix serving as both a panel sponsor and exhibitor, booth №12 is sure to be a bustling hub. We are excited to see the connections they forge develop into lasting partnerships down the line! PartnerMatrix invites all attendees of the AffPapa Conference Madrid 2026 to visit booth №12 to network, connect, and discuss potential collaborative partnerships. This article is provided by a third-party. AsiaGameHub (https://asiagamehub.com/) makes no warranties regarding its content. AsiaGameHub delivers targeted distribution for iGaming, Casino, and eSports, connecting 3,000+ premium Asian media outlets and 80,000+ specialized influencers across ASEAN.
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MGM+ 默默发布了一个令人困惑的新季,这是其最意外成功的科幻系列 Business

MGM+ 默默发布了一个令人困惑的新季,这是其最意外成功的科幻系列

(SeaPRwire) - 在ABC史上最傑出的經典懸疑科幻影集《Lost》大獲成功後,湧現了一波同類型影集,紛紛嘗試複製同樣的「謎題盒」公式。事實上,直到現在我們仍處在這波風潮當中,像是《Silo》和《Yellowjackets》都是這類作品。不過多年來,有一部影集一直悄悄是《Lost》眾多延伸作品中最出色的:那就是MGM+的《From. 和《Lost》一樣,這部民間恐怖影集擁有封閉、令人窒息的場景,也同樣有一個從未完全揭曉的持續謎團。但最重要的是,它找來了曾出演《Lost》的哈羅德·佩里諾(Harold Perrineau):他在ABC的《Lost》飾演施工經理麥可,在《From》則飾演小鎮領袖博伊德。這部影集圍繞著一座從未命名的小鎮展開,迷路的漂泊旅人誤入此地後就再也離不開。更可怕的是,夜晚有怪物出沒遊蕩,迫使小鎮居民必須團結求生,設法逃出生天,也許最終能找到回家的路。 佩里諾告訴Inverse:「名義上它是恐怖影集,但實際上是一齣人物刻劃研究。它講述一群人身處絕望處境,被困在一座小小的鎮上,還隨時被獵殺。」《From》第三季絕對是懸疑/恐怖影集結局的典範,不但揭開了關鍵超自然元素,還拉高了危機感、翻轉了現狀。但這部影集的第四季卻常常在混雜焦慮、畏懼與痛苦的混亂泥潭中原地打轉,就連作為影集核心靈魂的博伊德也受到影響。佩里諾說:「博伊德必須撐下去繼續前進。你要怎麼辦到這點?這就是他現在正在走的旅程。心智、平靜、肉身、靈魂都破碎了,但他必須繼續走,他其實沒有選擇。他的兒子在這裡,他愛的人都在這裡,他不得不走下去。」不過這一季還是有少數亮點。對於一部圍繞「進得去、出不來」的小鎮的影集來說,新登場的角色向來是重頭戲,這一季迎來了索菲亞(茱莉亞·道爾 Julia Doyle 飾演),她是牧師的女兒,她的天真對新觀眾來說是很好的切入點。 佩里諾說:「這一季,那個獵人只是稍微轉動了鑰匙,就讓緊張感再升高了一些。牠也許是你見過最邪惡的獵人,而那個獵人就是小鎮本身。」 《From》第四季有滿滿的驚嚇橋段。 | MGM+他說的沒錯:第四季的反派換上了全新形態,而且是今年電視圈最令人不寒而慄的反派之一。不過這個反派根本比不上滲透《From》每一個畫面的偏執氛圍。佩里諾說:「信任是劇中常常提到的東西,但這裡根本沒有信任可言。沒有任何地方是安全、舒適或者值得信任的,因為就算你以為自己待在安心的地方,你也必須問自己:『我的頭腦還清楚嗎?』因為你連自己的心智都不能相信。」 佩里諾表示,他詮釋博伊德的核心圍繞一個問題:「為什麼要繼續走下去?」這不會是永無止境的僵局。對於帶有龐大懸念衝突的影集來說,最終的解方就是收尾進入結局篇。而《From》已經獲得續訂第五季也就是最終季,看起來它終於要往最終結局的方向前進了。《From》現已於MGM+上線播出。本文由第三方廠商內容提供者提供。SeaPRwire (https://www.seaprwire.com/)對此不作任何保證或陳述。 分類: 頭條新聞,日常新聞 SeaPRwire為公司和機構提供全球新聞稿發佈,覆蓋超過6,500個媒體庫、86,000名編輯和記者,以及350萬以上終端桌面和手機App。SeaPRwire支持英、日、德、韓、法、俄、印尼、馬來、越南、中文等多種語言新聞稿發佈。
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邁威生物啟動港股招股:研發創新為核心 多元化管線佈局打造長期增長曲線 ACN Newswire

邁威生物啟動港股招股:研發創新為核心 多元化管線佈局打造長期增長曲線

香港, 2026年4月20日 - (亞太商訊 via SeaPRwire.com) - 生物醫藥產業是國家戰略性新興產業的核心組成部分,也是守護人類生命健康的關鍵屏障,邁威生物作為行業內領先企業,於4月20日正式啟動招股程式,距港交所上市再進一步。研發創新持續加碼,構築差異化競爭壁壘據悉,成立於2017年的邁威生物,是一家以藥物研發方面的創新能力以及從藥物發現至商業化銷售的綜合能力而聞名的中國製藥公司。公司擁有雄厚的自主創新能力,專注於打造可有效應對臨床挑戰的差異化產品,以技術創新突破臨床治療瓶頸,為患者帶來更優質、更高效的治療選擇。抗體偶聯技術創新,是邁威生物於 ADC 領域的核心優勢,亦是公司構建差異化競爭力的關鍵支撐。公司長期深耕 ADC 技術研發,已搭建起具備自主智慧財產權的四大核心ADC技術,涵蓋DARfinity、IDconnect、Mtoxin及LysOnly,具體而言,DARfinity為公司自主研發的定點偶聯工藝;IDconnect是一種經過優化設計的連接子分子,用以連接抗體和毒素,使抗體和毒素之間的連接更穩定;Mtoxin為一種基於喜樹堿的新型毒性分子,用作ADC中殺死靶細胞的「彈頭」;LysOnly則是一種能夠有條件釋放毒素的結構,可提高ADC的整體安全性和有效性。這四大核心ADC技術形成完備的技術體系,為產品管線持續反覆運算升級築牢堅實基礎。依託核心技術優勢,邁威生物構建了一組多元化的創新ADC產品管線,包括9MW2821、7MW3711和7MW4911等重點候選產品,每種產品針對不同的腫瘤相關抗原,精准覆蓋不同類型腫瘤的治療需求,形成了全面的產品矩陣。其中,為克服尿路上皮癌、三陰性乳腺癌、宮頸癌和食管癌治療的局限性,邁威生物開發了9MW2821,這是一款靶向Nectin-4的新一代ADC,可作為單藥亦或聯合療法中的主要藥物。相較於已上市的Padcev,9MW2821在尿路上皮癌患者的治療中展現出更優的療效,同時憑藉獨特的技術優勢,有望成為針對三陰性乳腺癌、宮頸癌和食管癌的同類型最佳靶向Nectin-4 ADC,市場前景廣闊,將為公司帶來顯著的業績增長動力。此外,7MW3711是一款靶向B7-H3 ADC,主要用於治療晚期實體瘤,國家藥監局於2023年7月批准7MW3711針對晚期實體瘤患者的臨床試驗的IND申請,標誌著該產品正式進入中國臨床開發階段;FDA於2024年2月批准7MW3711在美國進行臨床開發,並於2024年7月授予用於治療小細胞肺癌的ODD,為產品在美國市場的後續開發與商業化奠定了堅實基礎。公司分別於2023年8月及2023年9月,在中國啟動7MW3711單藥用於治療晚期實體瘤患者的兩項I/II期臨床試驗,進展順利;於2026年2月,啟動7MW3711聯合JS207(PD-1)或JS207及抗腫瘤療法,治療晚期實體瘤患者的Ib/II期臨床試驗,進一步拓展產品的應用場景,鞏固公司在ADC領域的領先地位。7MW4911是特異性靶向CDH17的新一代ADC,臨床前研究表明,7MW4911能有效結合腫瘤細胞上的CDH17,引發快速內化,並選擇性釋放細胞毒性載荷,從而最大程度減少對正常組織的損傷,安全性與有效性均表現優異。對於針對晚期實體瘤的7MW4911單藥療法,公司於2025年11月在中國啟動I期臨床試驗,並於2026年1月在美國啟動I/II期臨床試驗,加速推進產品的全球臨床佈局,未來將為公司全球化發展注入新的活力,進一步擴大公司的市場影響力。深耕單抗領域,拓展業務領域除ADC領域外,邁威生物在單抗領域亦不斷深耕與創新,多款管線產品均針對前景廣闊但較少探索的靶點,填補臨床治療空白。公司的關鍵產品9MW1911是一款靶向ST2的單抗,旨在治療COPD、哮喘和特應性皮炎等自身免疫性疾病,精准切入未被滿足的臨床需求領域。截至最後實際可行日期,全球尚無針對非Th2通路表型COPD的生物療法獲得批准,9MW1911作為在中國臨床開發階段進展最快的,首款自主研發靶向非Th2通路大分子藥物。從市場前景來看,中國COPD藥物市場規模龐大,市場規模從2019年的人民幣199億元增長到2024年的人民幣223億元,複合年增長率為2.3%,預計將加速增長至2028年的人民幣262億元及2032年的人民幣584億元,2024年至2028年及2028年至2032年的複合年增長率分別為4.0%及22.2%,行業具備著廣闊成長空間,9MW1911有望打開臨床治療缺口,為廣大COPD患者帶來新的治療希望。此外,9MW3811是用於纖維化相關疾病及癌症治療的靶向IL-11的人源化單抗,公司對9MW3811的Fc區實施化學修飾,以降低Fc介導毒性的潛在風險並延長其半衰期,進一步提升產品的安全性與療效,彰顯公司在單抗領域的研發實力與創新理念,為公司構建多元化的產品管線、拓展業務邊界提供了有力支撐。值得注意的是,此前因該品種IL-11在抗衰老方面的潛力,邁威生物已將其除大中華區以外的所有區域獨家開發、生產和商業化的權利授予Calico Life Sciences LLC,根據合作協定,公司將獲得一次性不可退還的首付款2500萬美元、合計最高達5.71億美元的近期、開發及商業化里程碑付款以及按淨銷售額計算的特許權使用費。據悉,Calico是一家美國公司及Alphabet Inc.的子公司,專注于創新型抗衰老療法的研發,並在涉及IL-11療法的抗衰老藥物開發方面具有豐富經驗。總體而言,邁威生物憑藉深厚的研發積澱、自主創新的核心技術、多元化的優質產品管線以及完善的商業化佈局,在行業內建立了堅實的行業地位,展現出強勁的增長潛力。此次赴港上市,公司有望借助資本市場的力量,加速推進核心產品的臨床開發與商業化進程,拓展國內外市場份額,提升綜合實力與核心競爭力,進而打開長期成長空間。 Copyright 2026 亞太商訊 via SeaPRwire.com. All rights reserved. www.acnnewswire.com
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東方證券與上海證券籌劃合併重組 加快推進一流現代投資銀行建設

香港, 2026年4月20日 - (亞太商訊 via SeaPRwire.com) - 4月19日下午,東方證券A股發佈籌劃重大事項的停牌公告,稱公司正在籌劃通過發行A股股份及支付現金方式收購上海證券100%股權事宜,東方證券A股股票將於4月20日開市起停牌,預計停牌時間不超過10個交易日。上海證券註冊資本為53.27億元,其中,百聯集團有限公司持有其50%股權,國泰海通證券股份有限公司持有其24.99%股權,上海國際集團投資有限公司持有其16.33%股權,上海國際集團有限公司持有其7.68%股權、上海城投(集團)有限公司持有其1.00%股權。4月19日,東方證券與前述股東簽署意向協議,擬以發行股份及部分現金支付方式收購前述股東所持上海證券的全部股權。近年來,新「國九條」等政策紅利持續釋放,支持頭部機構通過併購重組、組織創新等方式提升核心競爭力。在此背景下,證券行業併購重組活躍度顯著提升。本次合併重組立足服務國家戰略和上海國際金融中心建設大局,是推動上海金融國資佈局優化、深化金融國資國企改革,加快推進一流現代投資銀行建設的重要舉措。東方證券成立於1998年,於2015年、2016年先後實現A股與H股兩地上市,是上海本土重要綜合類券商,第一大股東申能集團持股26.63%。東方證券在全國設有170家分支機構,全資持有東證資管、東證期貨、東證資本、東證創新、東方香港等專業子公司,並作為第一大股東參股匯添富基金。2025年末,東方證券資產總額4,868.8億元,淨資產826.9億元;2025年實現營業收入153.6億元,歸母淨利潤56.3億元。上海證券成立於2001年,目前在境內設有分支機構80餘家,主要分佈於上海、浙江、江蘇、廣東、北京等地。2025年末,上海證券總資產957.7億元,淨資產198.1億元;2025年實現營業收入34.3億元,歸母淨利潤13.2億元。本次合併重組預計將形成良好的業務互補與協同效應,推動合併後的東方證券綜合競爭能力和行業地位持續提升,合併後的東方證券資產總額有望突破6,000億元,進入行業前十,淨資產突破1,000億元,分支機構數量將增加至250家左右。隨著渠道融合、產品協同的推進,東方證券獲取優質資產的能力得到提升,業務規模加速擴張,財富管理和資產管理等核心業務將進一步做大做強。此外,東方證券此次引入百聯集團、上海國際集團等戰略股東,有助於其在資本實力、產融協同與治理效能上不斷夯實邁向一流現代投資銀行的根基。東方證券公告最後稱,本次交易尚處於籌劃階段,相關事項尚存在不確定性,存在因為市場變化、監管審核、交易各方未能協商一致等各種原因無法達成或實施的風險。 Copyright 2026 亞太商訊 via SeaPRwire.com. All rights reserved. www.acnnewswire.com
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From the Heart: Discover Taiwan’s 19 Hot Spring Regions and Embark on Asia’s Most Restorative Mountain and Coastal Spa Journey SeaPRwire

From the Heart: Discover Taiwan’s 19 Hot Spring Regions and Embark on Asia’s Most Restorative Mountain and Coastal Spa Journey

April 20, 2026 – (SeaPRwire) – Positioned at the heart of East Asia and surrounded by the Pacific Ocean, Taiwan is emerging as one of Asia’s most compelling wellness travel destinations, offering a rare combination of geological diversity, cultural depth, and accessible luxury. Welcome to Taiwan and its richly diverse island-wide hot spring experience. Among its most distinctive natural assets are its hot springs. Formed by volcanic activity and deep mountain geology, Taiwan’s hot springs are rich in minerals known to support relaxation and overall wellbeing. For international travellers, these are not simply bathing destinations, but immersive experiences that combine nature, culture, and lifestyle. Taiwan is home to 19 officially recognised hot spring regions, each defined by unique mineral compositions and surrounding landscapes. From sulphur-rich volcanic springs to clear sodium bicarbonate waters, the diversity of spring types places Taiwan among the most varied hot spring destinations in the world. Two locations in particular have gained international attention. Tai’an Hot Spring in Miaoli and Jiaoxi Hot Spring in Yilan were both honoured with the 2025 “Top Ten Springs, Top Ten Beauties” Gold Award, one of Taiwan’s highest recognitions in the hot spring sector. Nestled within forested mountains, Tai’an offers a tranquil retreat known for its smooth, skin-enhancing waters and strong connection to indigenous culture. Jiaoxi, located on a rare flatland hot spring zone, is widely recognised for its unique alkaline spring quality and convenient access to urban infrastructure, making it especially attractive for short-stay international visitors. Across the island, hot spring temperatures average around 40°C, providing a consistently comfortable and restorative experience. From northern mountain ranges to southern coastal regions, travellers can experience hot spring bathing throughout all four seasons, positioning Taiwan as a year-round wellness destination. Accessibility is another key advantage. Taiwan’s integrated transport network, including High-Speed Rail, Taiwan Railways, and the Taiwan Tourist Shuttle, allows visitors to travel efficiently between cities and remote hot spring areas. This infrastructure enables flexible itineraries that cater to both short visits and extended stays. Accommodation options are equally diverse. International travellers can choose from premium five-star hot spring resorts, boutique design hotels, and locally operated guesthouses, offering a wide spectrum of experiences across different price points. In addition to its natural springs, Taiwan’s culinary landscape enhances the overall travel experience. Each hot spring region is closely connected to local agricultural produce and regional cuisine. Visitors can enjoy mountain-grown ingredients, fresh coastal seafood, and Taiwan’s globally recognised street food culture, creating a holistic journey that integrates wellness and gastronomy. Taiwan’s 19 hot spring regions are distributed across the island: Northern Taiwan: New Beitou,Shamao Mountain,Yangmingshan,Wulai,Jinshan-Wanli, Jiaosi, NeiwanJianshi Central Taiwan: Taian, Guguan, Dakeng, Wuri, Beigang Rivers, Dongpu Southern Taiwan: Guanzihling, Baolai, Sichong River, Eastern Taiwan: Antong, Rueisuei, Jhihben As global travellers increasingly seek destinations that offer both physical relaxation and cultural depth, Taiwan is extending a clear invitation to Southeast Asia. With its combination of natural resources, modern infrastructure, and diverse experiences, Taiwan presents a compelling new choice for wellness-focused travel in the region. Travellers are encouraged to explore Taiwan at their own pace and experience the island’s unique blend of warmth, nature, and hospitality.
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From the Heart: Discover Taiwan’s 19 Hot Spring Regions and Embark on Asia’s Most Restorative Mountain and Coastal Spa Journey ACN Newswire

From the Heart: Discover Taiwan’s 19 Hot Spring Regions and Embark on Asia’s Most Restorative Mountain and Coastal Spa Journey

TAIWAN, Apr 20, 2026 - (ACN Newswire via SeaPRwire.com) - Positioned at the heart of East Asia and surrounded by the Pacific Ocean, Taiwan is emerging as one of Asia's most compelling wellness travel destinations, offering a rare combination of geological diversity, cultural depth, and accessible luxury.Welcome to Taiwan and its richly diverse island-wide hot spring experience.Among its most distinctive natural assets are its hot springs. Formed by volcanic activity and deep mountain geology, Taiwan's hot springs are rich in minerals known to support relaxation and overall wellbeing. For international travellers, these are not simply bathing destinations, but immersive experiences that combine nature, culture, and lifestyle.Taiwan is home to 19 officially recognised hot spring regions, each defined by unique mineral compositions and surrounding landscapes. From sulphur-rich volcanic springs to clear sodium bicarbonate waters, the diversity of spring types places Taiwan among the most varied hot spring destinations in the world.Two locations in particular have gained international attention. Tai'an Hot Spring in Miaoli and Jiaoxi Hot Spring in Yilan were both honoured with the 2025 "Top Ten Springs, Top Ten Beauties" Gold Award, one of Taiwan's highest recognitions in the hot spring sector.Nestled within forested mountains, Tai'an offers a tranquil retreat known for its smooth, skin-enhancing waters and strong connection to indigenous culture. Jiaoxi, located on a rare flatland hot spring zone, is widely recognised for its unique alkaline spring quality and convenient access to urban infrastructure, making it especially attractive for short-stay international visitors.Across the island, hot spring temperatures average around 40°C, providing a consistently comfortable and restorative experience. From northern mountain ranges to southern coastal regions, travellers can experience hot spring bathing throughout all four seasons, positioning Taiwan as a year-round wellness destination.Accessibility is another key advantage. Taiwan's integrated transport network, including High-Speed Rail, Taiwan Railways, and the Taiwan Tourist Shuttle, allows visitors to travel efficiently between cities and remote hot spring areas. This infrastructure enables flexible itineraries that cater to both short visits and extended stays.Accommodation options are equally diverse. International travellers can choose from premium five-star hot spring resorts, boutique design hotels, and locally operated guesthouses, offering a wide spectrum of experiences across different price points.In addition to its natural springs, Taiwan's culinary landscape enhances the overall travel experience. Each hot spring region is closely connected to local agricultural produce and regional cuisine. Visitors can enjoy mountain-grown ingredients, fresh coastal seafood, and Taiwan's globally recognised street food culture, creating a holistic journey that integrates wellness and gastronomy.Taiwan's 19 hot spring regions are distributed across the island:● Northern Taiwan: New Beitou,Shamao Mountain,Yangmingshan,Wulai,Jinshan-Wanli, Jiaosi, NeiwanJianshi● Central Taiwan: Taian, Guguan, Dakeng, Wuri, Beigang Rivers, Dongpu● Southern Taiwan: Guanzihling, Baolai, Sichong River, Eastern Taiwan: Antong, Rueisuei, JhihbenAs global travellers increasingly seek destinations that offer both physical relaxation and cultural depth, Taiwan is extending a clear invitation to Southeast Asia. With its combination of natural resources, modern infrastructure, and diverse experiences, Taiwan presents a compelling new choice for wellness-focused travel in the region.Travellers are encouraged to explore Taiwan at their own pace and experience the island's unique blend of warmth, nature, and hospitality. Copyright 2026 ACN Newswire via SeaPRwire.com. All rights reserved. www.acnnewswire.com
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華大北斗亮相2026「飛向深空」航天大會 展望低軌衛星通導芯片新機遇 ACN Newswire

華大北斗亮相2026「飛向深空」航天大會 展望低軌衛星通導芯片新機遇

香港, 2026年4月20日 - (亞太商訊 via SeaPRwire.com) - 2026年4月16日至17日,「飛向深空」國際科創合作發展論壇在香港理工大學隆重舉辦,商業航天與低軌衛星領域備受資本市場矚目。作為國內知名空間定位服務提供商,華大北斗携《低軌衛星通導一體化時代的芯片機遇與商業化前景》主題演講亮相論壇,深度展望行業發展新機遇,充分彰顯其在衛星導航芯片領域具備突出的技術優勢與長期成長確定性。華大北斗董事長孫中亮:低軌衛星通導一體化迎來歷史性機遇國家「十五五」規劃明確提出,統籌建設衛星通信、導航、遙感系統,加快低軌衛星互聯網組網,構建空天地一體、通導感算融合的綜合服務體系。低軌衛星通導一體化服務,正從技術構想走向規模化應用。華大北斗董事長孫中亮在論壇演講中指出,技術演進推動衛星通信與衛星導航深度融合,基於低軌星座的「無網實時通信+高精度定位」通導一體化服務,可構建全域覆蓋、穩定可靠、低成本的時空信息服務體系,全面滿足行業應用與大眾消費的廣泛多元需求。孫中亮亦在會中表示,中國擁有獨具特色的通導一體化發展路徑,可依托現有北斗短報文通信與高精度定位技術開展前期應用驗證,為低軌通導融合開展技術預研與場景試驗。當前低軌星座進入密集組網階段,作為產業核心底座的芯片需求持續攀升,技術呈現集成化、小型化、低功耗發展趨勢,衛星導航定位芯片企業既迎來歷史性發展機遇,亦面臨技術突破與生態構建的雙重挑戰。技術領先築牢壁壘 全場景應用覆蓋廣闊市場 成長空間持續打開據悉,華大北斗已於2025年12月向港交所遞交招股書。華大北斗長期專注於GNSS導航定位芯片、模組及相關解決方案的研發和應用,產品全方位賦能智能手機、可穿戴設備、物聯網、交通管理、共享單車、智能駕駛和環境監測等多樣化場景。招股書顯示,公司已成長為全球第六、中國內地第二的GNSS空間定位服務提供商,並在雙頻高精度射頻基帶一體化芯片領域占據領先市場份額。公司堅持自主創新,持續推進產品迭代升級,完善產品矩陣,以高性能、高可靠、低功耗的芯片級解決方案,為通導一體化發展落地築牢核心技術基礎。隨著衛星互聯網建設提速、北斗應用規模化推進,衛星導航芯片行業進入高景氣週期。華大北斗作為國內稀缺的高精度導航芯片龍頭廠商,兼具技術壁壘與全場景落地能力,有望充分受益行業紅利。華大北斗憑藉在導航芯片領域的長期積累,正深度切入低軌通導一體化賽道,未來在商業航天與時空信息服務領域的增長動能充足,發展前景備受市場期待。 Copyright 2026 亞太商訊 via SeaPRwire.com. All rights reserved. www.acnnewswire.com
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洲際船務(2409.HK)雙輪驅動抗週期 業績逆勢增長可期

香港, 2026年4月20日 - (亞太商訊 via SeaPRwire.com) - 2025年全球航運市場持續受壓,行業整體陷入收入下滑、盈利承壓的普遍困境,而洲際船務(2409)憑藉「航運+船舶管理」雙輪驅動的獨特商業模式,成功實現業績逆勢突圍。公司雙業務協同發力,業績表現遠勝行業整體水平。全年總收入同比增長14.8%至3.24億美元,其中週期性較強的航運服務收入,在同期BDI及BCTI均值同比分别下跌4.2%和18.5%的背景下,僅微跌3.1%至1.99億美元,展現出較強的抗周期韌性;船舶管理業務更是核心增長引擎,全年收入飆升62.5%至1.25億美元,分部溢利增長45.9%,利潤率穩定維持在11.0%,公司於2025年連續三年入選勞氏日報全球十大船舶管理企業及管理者榜單,該業務擁有穩定現金流、低波動的核心屬性,有效對沖航運行業週期風險。航運服務板塊同樣憑藉戰略調整實現經營韌性突破,公司逆勢擴張推進船隊年輕化戰略,2025年綜合運力達170萬載重噸,同比增長38.21%,年內新增運力約80.7萬載重噸,涵蓋新造船、二手船、光租及投資船舶等多元模式。船隊平均船齡從6.0年大幅降至3.6年,遠低於全球行業13.1年的平均水平,不僅大幅降低油耗與後期維護成本,更能契合最新環保運營要求,疊加控制船舶利用率高達98.54%,整體運營效率持續領先行業。2025年公司以約4.82億元人民幣收購中集鑫德租賃40%股權,正式切入船舶租賃環節,成功打通「船舶投資、運營、管理、租賃」全產業鏈條。這一戰略佈局不僅實現與造船、融資租賃資源的深度協同,更提升一站式綜合服務能力,增強客戶粘性與議價權,提升抗周期能力,構建「經營+資本」雙輪盈利模式;年內出售6艘船舶錄得3,304萬美元收益,體現有序處置、價值釋放的資本管理節奏。通過恆常的船舶資產投資及營運活動,公司也得以在穩定的業務基礎上,產生額外財務收益,實現資本增值。公司船隊擴容動作持續落地,後續業績增長確定性拉滿。截至2025年底,公司在手在建船舶44艘,合計新增運力超122萬載重噸,當中預計2026年將有20艘新船陸續交付,為未來2至3年業績增長打下扎實基礎。股價走勢方面,截至2026年4月15日收盤,公司股價報4.14港元,近三個月維持4.0至4.2港元區間震蕩,走勢抗跌性極強。當前市盈率(TTM)僅7.4倍,處於歷史相對低位,估值具備充足安全邊際,風險回報具一定吸引力。 Copyright 2026 亞太商訊 via SeaPRwire.com. All rights reserved. www.acnnewswire.com
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邁威生物赴港上市:核心ADC產品臨床領先 國際化佈局提速

香港, 2026年4月20日 - (亞太商訊 via SeaPRwire.com) - 4月20日,主打創新藥研發的邁威生物(Mabwell)啟動招股程式,擬於聯交所主機板掛牌。繼2022年登陸科創板後,這家成立於2017年的藥企即將完成「A+H」雙資本平臺佈局。公司核心產品9MW2821是一款靶向Nectin-4的ADC藥物。根據弗若斯特沙利文的資料,截至最後實際可行日期,就臨床開發階段而言,9MW2821是在中國開發的用於治療尿路上皮癌的所有靶向Nectin-4 ADC中進展最快的,在全球僅次於Padcev(唯一經FDA批准的靶向Nectin-4 ADC)。同時,9MW2821亦是全球首款進入宮頸癌關鍵III期臨床試驗的同靶點ADC藥物,並已獲FDA多項快速通道及孤兒藥資格認定。邁威生物擁有自主ADC技術平臺(IDDC),目前已建立包含4款上市產品(如邁利舒®、邁粒生®)及10款候選藥物的管線。2025年收入同比大增230%至6.6億元人民幣,主要得益於對外授權收入及核心產品銷量增長;年內虧損同比收窄7.1%; 毛利達5.96億元。2025年,公司研發成本為9.8億元,同比增長24.8%。截至最後實際可行日期,公司已在全球範圍內獲得147項專利並提交271份專利申請,包括與核心產品有關的27項專利及15份專利申請。公司已在江蘇泰州建有2個生產基地,其中,抗體和重組蛋白中試及商業化生產基地符合中國GMP標準及歐盟EMA GMP標準,承擔多個已上市品種的國內外商業化生產;ADC藥物商業化生產基地設有2條ADC抗體原液生產線、2條ADC原液生產線及1條ADC產品製劑生產線。此外,位於上海金山、符合歐盟EMA GMP標準的大規模商業化生產基地正在建設中,已進入試生產階段,為後續全球臨床及商業化供應提供保障。此次H股上市,邁威生物擬將募資主要用於核心產品9MW2821的臨床試驗、其他腫瘤及年齡相關疾病管線的研發。 Copyright 2026 亞太商訊 via SeaPRwire.com. All rights reserved. www.acnnewswire.com
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Fujitsu launches GLOVIA One ERP solution for mid-sized Japanese enterprises JCN Newswire

Fujitsu launches GLOVIA One ERP solution for mid-sized Japanese enterprises

KAWASAKI, Japan, Apr 20, 2026 - (JCN Newswire via SeaPRwire.com) - Fujitsu Limited today announced the integration of its GLOVIA ERP solution lineup, combining its accounting, human resources and payroll, sales, and production domains into GLOVIA One, with sequential availability starting April 22, 2026. GLOVIA One primarily targets Japanese companies with annual sales ranging from approximately 3 billion yen to 100 billion yen. It is a core business ERP solution designed to flexibly adapt to Japan's unique business processes, commercial practices, legal systems, and future business growth and changes, allowing for phased evolution. Furthermore, it provides a function to integrate and visualize data through an AI agent, supporting human decision-making.Many mid-sized Japanese companies face challenges such as labor shortages and digital disparities. To address these issues, Fujitsu will deploy GLOVIA One as an AI-era ERP solution, supporting business growth by advancing management in response to environmental changes, based on its Uvance business model, which addresses societal challenges.GLOVIA One will be provided in a multi-tenant configuration via the cloud. Fujitsu redesigned the architecture to enable API-based integration with third-party solutions, thereby minimizing add-on development and allowing for the selection of optimal solution functions without dependence on specific vendors or services. Moreover, by operating on the Uvance Platform, a common platform supporting Uvance, it realizes high security and efficient, stable operation management, providing a flexible foundation to adapt to a rapidly changing business environment.GLOVIA One Concepts and FeaturesGLOVIA One aims to achieve "co-evolution" through three core concepts: INSIGHT, FIT TO JAPAN, and PARTNERSHIP. This approach fosters a cycle of continuous innovation by integrating ongoing improvements and insights from various companies, leading to evolving management and operations.1. INSIGHT: Management and operational judgment to guide the next stepGLOVIA One centralizes accounting, human resources and payroll, sales, production, and other related business data in a single data lake, then integrates and visualizes data using AI. In the future, it will also provide a Chat BI [1] function, an AI agent that analyzes business data from multiple perspectives and supports decision-making. Chat BI will provide answers, implications, and options in real time—beyond analysis alone.2. FIT TO JAPAN: An ERP that continuously evolves within Japanese business environmentsRather than enforcing uniform processes through a fit to standard approach, GLOVIA One is designed based on Clean Core [2] , enabling customer-specific improvements, innovations, and operational knowledge cultivated in Japanese business environments to coexist with the product functionality.GLOVIA One integrates the existing GLOVIA SUMMIT, GLOVIA iZ, and GLOVIA Kirara lineups, and standardizes key business rules, design principles, and setup procedures. Furthermore, by maintaining the core standard functions, Fujitsu enables an architecture that automates future upgrades and function updates. This approach aims to provide functions optimized for each customer’s operations without forcing disruptive process changes. Additionally, Fujitsu will incorporate AI agents into its GLOVIA One development, implementation, and maintenance to accelerate the release of standard functions. This will help customers respond to Japan-specific commercial practices and tax reforms without interrupting operations.3. PARTNERSHIP: Sustainable growth born from connectionsThrough PARTNERSHIP in GLOVIA One, industry and business knowledge will be implemented across the entire ecosystem as AI agents and functions, and their value will be shared, deployed, and accumulated within the community.Fujitsu will openly share a composable architecture that combines functions, data, and external services via APIs. AI agents that understand business context will link decision-making to execution, helping automate business processes optimized for each customer. By building on these co-creation efforts, Fujitsu will form a Japan-born ERP ecosystem designed for Japan that continuously redefines what ERP can be.Future PlansTo address societal challenges such as labor shortages and digital disparities, Fujitsu will expand its composable business foundation, centered on GLOVIA One, enabling flexible responses to diverse business requirements across companies and industries.Furthermore, by the end of fiscal year 2026, Fujitsu will begin offering Chat BI, an AI agent that leverages data and AI to support decision-making. Concurrently, through connections with stakeholders possessing industry knowledge, Fujitsu will continuously promote the integration of external solutions tailored to specific industry characteristics, thereby establishing an environment where business functions can be selected and combined.Looking ahead, under the Uvance business model, which aims to address societal challenges, AI agents that understand the entire business workflow will collaborate with external solutions and services to provide one-stop support from decision-making to execution, thereby advancing the sustainable growth and strengthening of industrial competitiveness for Japanese companies.[1] Chat BI:A business intelligence (BI) function that uses AI to provide analysis and insights into business and management data in a conversational format.[2] Clean Core:A concept of maintaining the core ERP system without modifications.About FujitsuFujitsu’s purpose is to make the world more sustainable by building trust in society through innovation. As the digital transformation partner of choice for customers around the globe, our 113,000 employees work to resolve some of the greatest challenges facing humanity. Our range of services and solutions draw on five key technologies: AI, Computing, Networks, Data & Security, and Converging Technologies, which we bring together to deliver sustainability transformation. Fujitsu Limited (TSE:6702) reported consolidated revenues of 3.6 trillion yen (US$23 billion) for the fiscal year ended March 31, 2025 and remains the top digital services company in Japan by market share. Find out more: global.fujitsuPress ContactsFujitsu LimitedPublic and Investor Relations DivisionInquiries Copyright 2026 JCN Newswire via SeaPRwire.com. All rights reserved. www.jcnnewswire.com
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教宗良十四世否認「暴君」言論針對特朗普 News

教宗良十四世否認「暴君」言論針對特朗普

(SeaPRwire) - 美國總統因這位教宗批評中東戰爭而猛烈抨擊這位宗座 教宗良十四世試圖緩和與唐納德·川普之間的公開爭執,否認外界指稱他藉由批評伊朗戰爭與呼籲和平來挑戰這位美國總統。 這位美國出生的宗座周六在搭機前往安哥拉的途中對記者表示,他的發言並非要引發對立,同時批評媒體透過過多評論與臆測放大這場爭端。 「有個特定說法在各方面都不夠準確……許多刊出的內容……不過是針對評論的評論,試圖解讀所說過的話,」這位教宗說道。他強調,本周稍早在喀麥隆發表的言論中,他譴責揮霍數十億美元於戰爭的領袖,並形容世界「被少數獨裁者摧殘」,這些話並非針對川普。 「然而,事實上人們卻認為我試圖與這位總統辯論,這根本不是我的意圖,」他說道。 儘管這位教宗過去曾批評川普的政策,包括大規模驅逐出境,以及川普將歐洲形容為「墮落」,但中東戰爭加劇了兩人之間的緊張關係。這位宗座呼籲各方「停止暴力惡性循環」,並稱川普摧毀伊朗文明的威脅「無法接受」。 在美國國防部長Pete Hegseth呼籲美國人祈禱「以耶穌基督之名」後,這位教宗也表示,上帝「不會聆聽發動戰爭者的祈禱」。 川普則反過來稱這位教宗「對犯罪軟弱,外交政策極為糟糕」,並補充說他不想要「批評美國總統的教宗」。 美國副總統J.D. Vance先前曾批評這位宗座,此次對良十四世的最新言論表示歡迎。 「我很感謝良教宗這麼說,」Vance周日在X上寫道。「儘管媒體的說法不斷挑起衝突——而且是的,確實存在過且將會出現真正的分歧—— 但現實往往複雜得多。」本文由第三方廠商內容提供者提供。SeaPRwire (https://www.seaprwire.com/)對此不作任何保證或陳述。 分類: 頭條新聞,日常新聞 SeaPRwire為公司和機構提供全球新聞稿發佈,覆蓋超過6,500個媒體庫、86,000名編輯和記者,以及350萬以上終端桌面和手機App。SeaPRwire支持英、日、德、韓、法、俄、印尼、馬來、越南、中文等多種語言新聞稿發佈。
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美國在西歐的影響力正在下降 News

美國在西歐的影響力正在下降

(SeaPRwire) - 跨大西洋依賴的神話正在出現裂痕 美國在與歐洲關係中的最大弱點很簡單:是華盛頓更需要這片大陸,而非大陸更需要華盛頓。 美國以二戰勝利者之一的身份來到歐洲。它在西部建立了軍事主導地位,將自身嵌入該地區的安全架構中,並在數十年裡將歐洲作為其對抗蘇聯的前沿基地。在此過程中,它也在1940年代末保護了西歐精英階層免受共產主義運動的威脅。然而,弔詭的是,這份恩情從未在柏林、巴黎或倫敦得到完全的諒解。 這種揮之不去的怨恨並不意味著西歐即將反抗其跨大西洋的保護者。其精英階層過於謹慎且牽涉太深,不會這麼做。但這確實意味著,每當美國顯現弱點時,這些歐洲人將會機會主義地、不帶感情地加以利用。 這一刻現在已經到來。 華盛頓近期的決策創造了一個西歐人已經開始利用的突破口。最明顯的跡象出現在英國首相基爾·斯塔默出人意料地排除了加入對伊朗海上封鎖的可能性。對於那些仍然相信跨大西洋聯盟牢不可破的人來說,這可能令人驚訝。實際上,這完全符合過去80年美國與西歐關係的邏輯。 該地區的其他主要大國很可能採取類似的謹慎態度。即使是美國的壓力威脅,包括談論削弱北約承諾,也不太可能迫使它們在荷姆茲海峽進行直接對抗。 西歐明白一個根本道理:沒有其在歐洲大陸的存在,美國將面臨地緣政治孤立的風險。那種認為北約存在主要是為了保護當地人免受外部威脅的熟悉說法,在很大程度上是一種方便的虛構。它掩蓋了一個更基本的現實,即正是華盛頓從維持這種「特殊關係」中獲得了最大的戰略利益。 首先,失去歐洲作為領土基地將從根本上改變美國與俄羅斯之間的戰略平衡。「灰色地帶」——即對抗可以發生而不會立即升級為對國家領土直接打擊的空間——將會消失。任何衝突都將立刻變得更加危險。 其次,美國將失去通過在俄羅斯邊境附近部署軍事資產(包括核能力)來向其施壓的能力。值得注意的是,俄羅斯在西半球沒有等同的機會。 第三,美國從歐洲撤軍將使任何與華盛頓進行的有意義的戰略對話,從莫斯科的角度來看變得越來越沒有意義,從而加速俄羅斯轉向中國。 換句話說,美國在歐洲的軍事存在並非慈善之舉。它是一項關鍵資產,是美國在與其他大國更廣泛競爭中的外交和戰略槓桿。 西歐領導人對此心知肚明。他們還明白另一點:美國的安全保證並不像通常描繪的那樣絕對。 即使在冷戰時期,歐洲也幾乎沒有人真正相信,美國會為了回應蘇聯對巴黎的打擊而犧牲紐約或波士頓。這種懷疑態度塑造了獨立的歐洲戰略,最顯著的是法國的核學說,該學說優先考慮對蘇聯城市的直接威懾,而非依賴美國的保護。 這種邏輯並未消失。甚至可以說,它變得更加相關了。 北約在冷戰後的擴張,將安全保證延伸到了戰略重要性遠低於英國、法國或德國的國家。與此同時,近期事件已經展示了美國力量的局限性。美國甚至無法完全保護小型海灣國家免受報復性打擊,這進一步加劇了對其安全保護傘可信度的懷疑。 幾十年來,跨大西洋關係基於一種默契運作:西歐假裝需要保護,而美國則假裝提供保護。這種安排對雙方都有利。 但當前的美國政府打破了這種平衡。其反覆無常的決策和狹隘的關注點造成了不確定性,並在此過程中給了西歐精英階層一個加強自身地位的機會。而他們正在抓住這個機會。 這並不意味著歐洲人正在脫離。兩個限制因素仍然具有決定性。首先,他們的經濟與美國金融和技術體系的深度融合,繼續限制著真正的自主性。通過歐元或歐盟單一市場來減少這種依賴的努力,只取得了部分成功。 其次,西歐各國政府仍然需要美國的力量來管理他們與俄羅斯複雜的關係。儘管當前存在對抗,但歷史上最終與莫斯科達成和解的記憶猶存。然而,就目前而言,迅速和解的誘因很少。 改變的是夥伴關係內部的平衡。這些歐洲精英階層,對自己管理國內民眾和應對外部壓力的能力充滿信心,現在看到了更大的迴旋餘地。他們將利用這一點來獲取讓步、重塑承諾,並對沖美國的不可預測性。 與此同時,華盛頓將自己置於一個困難的境地。它正試圖同時穩定與俄羅斯的關係、維持對西歐的控制,並為與中國的戰略對抗做準備。這些目標並不容易兼容。 結果是脆弱性,主要不是對莫斯科或北京的脆弱性,而是跨大西洋關係內部的脆弱性。通過自身的行動,美國給了其歐洲盟友一系列優勢。他們將謹慎但果斷地利用這些優勢。 尚不清楚的是,華盛頓打算如何重新奪回主動權,或者它是否完全明白自己將失去什麼。 本文首發於 Vzglyad 報紙,並由 RT 團隊翻譯編輯。本文由第三方廠商內容提供者提供。SeaPRwire (https://www.seaprwire.com/)對此不作任何保證或陳述。 分類: 頭條新聞,日常新聞 SeaPRwire為公司和機構提供全球新聞稿發佈,覆蓋超過6,500個媒體庫、86,000名編輯和記者,以及350萬以上終端桌面和手機App。SeaPRwire支持英、日、德、韓、法、俄、印尼、馬來、越南、中文等多種語言新聞稿發佈。
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30年前,一部邪典經典電視劇嘗試打入好萊塢卻以失敗收場 Business

30年前,一部邪典經典電視劇嘗試打入好萊塢卻以失敗收場

Gabe Ginsberg/Getty Images Entertainment/Getty Images(SeaPRwire) - 曾幾何時,並非所有的螢幕都是平等的。到了 1996 年,Mystery Science Theater 3000 已成為深夜有線電視中備受喜愛的支柱,並擁有忠實的邪典追隨者。它的第七季(如果算上 KTMA 時期的劇集則是第八季)才剛在 Comedy Central 播出。但在串流媒體時代之前,電視節目並不被視為「主流」——至少在電影的定義下是如此。Mystery Science Theater 3000 起源於明尼蘇達州的公共電視頻道,儘管在 Time Warner 的電視網播出,但其製作風格與好萊塢相去甚遠。對於未曾接觸過的觀眾來說,MST3K 是最早的電影吐槽節目,內容是一群聰明伶俐的木偶與一名普通人類主持人——前五季由創作者 Joel Hodgson 擔任,隨後由 Mike Nelson、Jonah Ray 以及現任主持人 Emily Marsh 接手——被囚禁在名為「Satellite of Love」的太空船上,被迫觀看低成本 B 級電影,作為節目中瘋狂科學家進行心智控制實驗的一部分。這正是 Manos: The Hands of Fate 以及其他數百部「垃圾電影」被介紹給品味獨特的觀眾的地方。該節目及其吐槽的電影皆非主流製作,這種「弱者」心態在節目的創意團隊中非常明顯。據編劇兼表演者 Kevin Murphy 在 2021 年所述,自從 Mystery Science Theater 3000 明顯「將會持續存在一段時間」後,編劇室裡就一直有將其轉化為大銀幕體驗的討論。但並非所有人都想進軍主流:在同一份口述歷史中,Hodgson 表示:「我離開節目的原因就是因為這部電影。當時存在創作分歧。」儘管如此,導演 Jim Mallon 仍堅持認為 MST3K 在大銀幕上會成功,因為「和你一起在房間裡觀看 Mystery Science 的人越多,就越有趣。」引用(其中一些相當冷門)是該節目幽默感的重要組成部分:從極具中西部特色的內部笑話,到向 Jacques Tati 和 Phillip Glass 等高雅藝術大師致敬,Mystery Science Theater 3000 拒絕以居高臨下的態度對待觀眾,也拒絕為了變得更通俗而稀釋其獨特性。直到 Universal Pictures 加入為止。雖然 Hodgson 在 1993 年離開節目之前曾與 Paramount 會面,但最終 Mystery Science Theater 3000: The Movie 還是落腳於 Universal。該公司引導團隊放棄了最初的想法——即將 Mike 與機器人之間的過場片段擴展為長篇敘事——轉而製作了一部基本上是將電視節目放大到電影銀幕上的作品。(諷刺的是,Mystery Science Theater 3000: The Movie 片長僅 78 分鐘,甚至比該節目的平均集數還要短。)該工作室還希望 MST3K 團隊吐槽一部工作室片庫中已有的電影;最終,他們選中了 1955 年的科幻電影 This Island Earth,該片由 Jeff Morrow、Rex Reason 和 Faith Domergue 主演。與大多數 MST3K 的選片不同,這部電影在最初上映時其實頗受影評人好評。然而回頭看,其飛碟和發光的綠色射線確實足夠滑稽,適合進行電影吐槽。Mike、Tom Servo、Crow 和 Gypsy 可能永遠沒能成為家喻戶曉的名字,但 Mystery Science Theater 3000: The Movie 仍然是決定該系列傳承的重要部分。 | Best Brains/Universal/Kobal/Shutterstock有趣的是,這部 86 分鐘的電影中,實際進入 Mystery Science Theater 3000: The Movie 的片段僅約 55 分鐘。吐槽內容也相當平淡,被工作室高層刪減,他們擔心會疏遠那些對流行文化知識不如 MST3K 死忠粉絲豐富的觀眾。例如,對 Parliament-Funkadelic 貝斯手 Bootsy Collins 的引用被刪除了,多個主持人片段和電影劇本的原始結局也被刪除。編劇兼聯合主演 Mary Jo Pehl 在 2021 年表示:「我們不習慣為笑話辯解或解釋。我認為這對我們來說真的很令人沮喪,因為我們的觀念是:如果你聽懂了,那很好;如果你沒聽懂,下一個笑話你就會懂了。我不認為我們習慣於被如此嚴格地審視。」因此,儘管粉絲們確實出現在首映週末,但 Mystery Science Theater 3000: The Movie 並未能將 MST3K 推向主流。它既不完全是為粉絲製作的,也不完全是為新手製作的。Universal 也幾乎沒有對這部電影進行宣傳,而是將當週所有的宣傳資源都投入到了 Pamela Anderson 主演的電影 Barbed Wire 上——這恰恰是 MST3K 團隊賴以成名的那種嘲諷對象。然而,並非一切都付諸東流。儘管 Mystery Science Theater 3000: The Movie 很少被列為該節目最偉大的集數之一——而它本質上確實就是該節目的一集——但它仍然為該系列帶來了新一代的粉絲。其中一位是未來的節目主持人 Jonah Ray,他在 2021 年表示:「我喜歡所有的節目,但這部電影是我心中非常深刻的記憶。」所以,雖然 Mystery Science Theater 3000: The Movie 沒有讓 Mike、Tom Servo、Crow 和 Gypsy 成為家喻戶曉的名字,但它確實為確保該節目的長壽盡了一份力,讓這部電影的 VHS 錄影帶在接下來的幾十年裡得以流傳。Mystery Science Theater 3000: The Movie 現已在 Tubi 上線。本文由第三方廠商內容提供者提供。SeaPRwire (https://www.seaprwire.com/)對此不作任何保證或陳述。 分類: 頭條新聞,日常新聞 SeaPRwire為公司和機構提供全球新聞稿發佈,覆蓋超過6,500個媒體庫、86,000名編輯和記者,以及350萬以上終端桌面和手機App。SeaPRwire支持英、日、德、韓、法、俄、印尼、馬來、越南、中文等多種語言新聞稿發佈。
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美國扣押伊朗國旗貨輪 — 特朗普 News

美國扣押伊朗國旗貨輪 — 特朗普

(SeaPRwire) - 美國總統表示,該船隻當時正試圖通過阿曼灣的美軍防線。 美國總統唐納·川普(Donald Trump)宣布,美國在阿曼灣扣押了一艘懸掛伊朗國旗的貨船,該船當時正試圖突破美國對伊朗實施的海軍封鎖。 「美國海軍導彈驅逐艦 USS SPRUANCE 在阿曼灣攔截了 TOUSKA 號,並給予其停止航行的明確警告,」川普週日在 Truth Social 上寫道。 「伊朗船員拒絕聽從,因此我們的海軍艦艇通過轟開其機艙,將他們攔截下來。」 後續詳情將持續更新 本文由第三方廠商內容提供者提供。SeaPRwire (https://www.seaprwire.com/)對此不作任何保證或陳述。 分類: 頭條新聞,日常新聞 SeaPRwire為公司和機構提供全球新聞稿發佈,覆蓋超過6,500個媒體庫、86,000名編輯和記者,以及350萬以上終端桌面和手機App。SeaPRwire支持英、日、德、韓、法、俄、印尼、馬來、越南、中文等多種語言新聞稿發佈。
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路易斯安那州枪击事件致八名儿童遇难–警方称 News

路易斯安那州枪击事件致八名儿童遇难–警方称

(SeaPRwire) - 官員將此事件描述為一起失控的家庭糾紛 警方表示,週日在路易斯安那州什里夫波特發生的大規模槍擊事件中,有八名兒童遇害,並將此次襲擊描述為一起升級為致命暴力的家庭糾紛。 根據社交媒體上的一份聲明,當地時間早上6點剛過(格林威治標準時間11:00),警方接到西79街300街區發生家庭騷亂的報告後趕往現場。發言人克里斯托弗·博爾德隆表示,暴力事件涉及多個地點。 「總共有三個不同的現場,」 博爾德隆說,並補充說最初的槍擊發生在西79街,隨後在哈里森街發生了相關事件,至少有一名受害者逃往鄰近的住所。 共有十人中槍,其中八人不幸身亡。受害者的年齡從18個月到15歲不等。 博爾德隆表示,嫌犯逃離了現場,並試圖劫持一輛車輛逃跑,隨後遭到警員追捕。警方在追捕後最終開槍擊斃了嫌犯。 當局尚未公布嫌犯的身份,也未提供除家庭糾紛之外的動機細節。 警察局長韋恩·史密斯表示,僅有的倖存者是兩名成年女性,其中一人情況仍然危及生命。據信其中一名女性與嫌犯有關係。史密斯說,一些中槍的兒童與嫌犯有親屬關係,並稱這是「一個大多數人從未見過的、範圍廣泛的現場。」 州警補充說,沒有警員在此事件中受傷。 「這是一個悲劇性的局面——可能是我們遇到過最糟糕的悲劇,」 什里夫波特市長湯姆·阿西諾說。「這是個可怕的早晨。」 網上流傳的報導指認嫌犯為沙馬爾·埃爾金斯,但官方尚未正式確認其身份。 本文由第三方廠商內容提供者提供。SeaPRwire (https://www.seaprwire.com/)對此不作任何保證或陳述。 分類: 頭條新聞,日常新聞 SeaPRwire為公司和機構提供全球新聞稿發佈,覆蓋超過6,500個媒體庫、86,000名編輯和記者,以及350萬以上終端桌面和手機App。SeaPRwire支持英、日、德、韓、法、俄、印尼、馬來、越南、中文等多種語言新聞稿發佈。
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